Effective Parameters on the Partition Coefficient of Guanidine Hydrochloride in the Poly (Ethylene Glycol) +Phosphate +Water System at 298.15 K

Rahimpour, F.; Pirdashti, M.

Effective Parameters on the Partition Coefficient of Guanidine Hydrochloride in the Poly (Ethylene Glycol) +Phosphate +Water System at 298.15 K

Document Type : Full article

Authors

F. Rahimpour ¹

M. Pirdashti ²

¹ Biotechnology Research Lab, Chemical Engineering Department, Faculty of Engineering, Razi University, Kermanshah, Iran

² Chemical Engineering Department, Faculty of Engineering, Shomal University, Amol, Iran

Abstract

The partition coefficient of guanidine hydrochloride for the PEG4000+ Phosphate +Water system is presented at 298.15 K. The partition coefficient of guanidine hydrochloride was near unity. It was shown that partition coefficient of guanidine
hydrochloride was dependent on the concentration of guanidine hydrochloride, pH and PEG/phase forming salt (%w/w) ratio. In most systems the partitioning coefficient of Guanidine is more than one, which means guanidine preferred polymer-rich phase.

Keywords

Aqueous Two Phase System

ATPS

Partition

Guanidine Hydrochloride